Enzymatic Vitrectomy http://floatertalk.yuku.com/forums/11 en-us Copyright 2006, Yuku feeds@yuku.com (FeedMaster) webmaster@yuku.com (WebMaster) Fri, 26 Dec 2008 17:58:56 GMT Fri, 04 Dec 2009 06:01:07 GMT Yuku Feeds 1.0 http://blogs.law.harvard.edu/tech/rss 60 Yuku http://static.yuku.com//feed/bypass/images/button-yuku.png http://floatertalk.yuku.com/forums/11 Yuku - free hosted forums and profiles 88 31 {pics-1.1 "http://www.icra.org/ratingsv02.html" l gen true for "http://yuku.com" r (nz 1 vz 1 lz 1 oz 1 cz 1 ) "http://www.rsac.org/ratingsv01.html" l gen true for "http://yuku.com" r (n 0 s 0 v 0 l 0 )) Search Search Domain q http://yuku.com/search/direct/ <![CDATA[ Vitreosolve clinical trials canceled. ]]> http://floatertalk.yuku.com/topic/3177/t/Vitreosolve-clinical-trials-canceled-.html http://clinicaltrials.gov...m=NCT00664183&rank=1

Maybe it wasn't going to be an answer, but it appears Vitreosolve has hit a snag at the very least. Another key wording is "interim analysis conducted" whatever that really means. I guess time will tell.
]]> feeds@yuku.com (avenger) http://floatertalk.yuku.com/topic/3177 Tue, 01 Dec 2009 02:47:43 GMT <![CDATA[ new to forum floater question ]]> http://floatertalk.yuku.com/topic/3174/t/new-to-forum-floater-question.html
I'm new to the forum -- how successful are FOVs? What about if the floaters are close to the retina? ]]> feeds@yuku.com (seekingadvice) http://floatertalk.yuku.com/topic/3174 Sun, 29 Nov 2009 20:20:00 GMT <![CDATA[ Dr Sebag Answers On Microplasmin ]]> http://floatertalk.yuku.com/topic/3023/t/Dr-Sebag-Answers-On-Microplasmin.html
His reply is below

=====

Microplasmin will be considered by the FDA for approval in cases with vitreo-macular traction, nothing else. If approved, I suspect that there will be those who attempt to use it 'off-label' to treat floaters. I don't know if the enzyme at the approved dose will be able to break down the floaters. A higher dose would probably not be safe, or at least we don't know about higher doses than those that were tested until a study... ]]> feeds@yuku.com (kalachakra1234) http://floatertalk.yuku.com/topic/3023 Tue, 18 Aug 2009 03:29:15 GMT <![CDATA[ Bottom Line ]]> http://floatertalk.yuku.com/topic/2970/t/Bottom-Line.html Let's say an enzyme comes around that perfectly induces PVD, and liquifies the vitreous. It makes sense that this is not enough to rid us of our floaters since the collegen would still exist. So, this is something that would help vitrectomies go far better with less risk.

However, the bottom line question is, even with this will our docotors stop telling us to live with our floaters? They've all told me vitrectomy is major surgery. They still have to perform major... ]]> feeds@yuku.com (avenger) http://floatertalk.yuku.com/topic/2970 Mon, 27 Jul 2009 18:12:19 GMT <![CDATA[ This is Important!! ]]> http://floatertalk.yuku.com/topic/2877/t/This-is-Important-.html
http://www.retinalphysician.com/article.aspx?article=102991

"An intriguing prospect is the combination of an agent causing vitreous liquefaction with one primarily acting as a PVD inducer. In an experimental rat model of diabetes, the induction of a PVD was significantly more effective when both plasmin and... ]]> feeds@yuku.com (kalachakra1234) http://floatertalk.yuku.com/topic/2877 Wed, 17 Jun 2009 07:14:38 GMT <![CDATA[ Interesting article on Microplasmin ]]> http://floatertalk.yuku.com/topic/2874/t/Interesting-article-on-Microplasmin.html Philip J. Polkinghorne discusses the potential of microplasmin as an enzyme to treat "vitreous opacities" (aka floaters). The article is very well done and reflects an impressive level of professionalism. It is encouraging to see that studies on floaters are gaining visibility in mainstream publications.

feeds@yuku.com (Bluford) http://floatertalk.yuku.com/topic/2874 Tue, 16 Jun 2009 20:25:46 GMT <![CDATA[ Vitreolase!!!!! Look like a promising cure for floaters!!!! ]]> http://floatertalk.yuku.com/topic/2793/t/Vitreolase-Look-like-a-promising-cure-for-floaters-.html
http://www.vitreoretinaltech.com/pdfs/Research%20Review.pdf

]]> feeds@yuku.com (kalachakra1234) http://floatertalk.yuku.com/topic/2793 Sun, 24 May 2009 11:10:44 GMT <![CDATA[ plasmin trials ]]> http://floatertalk.yuku.com/topic/2690/t/plasmin-trials.html feeds@yuku.com (floater9876) http://floatertalk.yuku.com/topic/2690 Tue, 31 Mar 2009 21:19:34 GMT <![CDATA[ 5 years later and maybe some hope ]]> http://floatertalk.yuku.com/topic/2682/t/5-years-later-and-maybe-some-hope.html feeds@yuku.com (floater9876) http://floatertalk.yuku.com/topic/2682 Tue, 24 Mar 2009 20:43:09 GMT <![CDATA[ IMPORTANT: Collagen and enzymes ]]> http://floatertalk.yuku.com/topic/2663/t/IMPORTANT-Collagen-and-enzymes.html
I am a fellow sufferer of floaters of the collagen type. They are very detailed, some of the floaters are very long, and even have "bubbles" in them. They also move around (but confined in a certain area), and are even FLEXIBLE, as in I can see them bend and change shapes if I move my eyeball.

I find the articles on enzymatic vitrectomy very interesting. However, I would like to remind you all that the floaters we are suffering from are made up of... ]]> feeds@yuku.com (sl) http://floatertalk.yuku.com/topic/2663 Tue, 17 Mar 2009 11:14:38 GMT <![CDATA[ Article about a German research project concerning Plasmin ]]> http://floatertalk.yuku.com/topic/2565/t/Article-about-a-German-research-project-concerning-Plasmin.html feeds@yuku.com (jlo) http://floatertalk.yuku.com/topic/2565 Fri, 23 Jan 2009 13:47:04 GMT <![CDATA[ MicroPlasmin Phase IIb Trial ]]> http://floatertalk.yuku.com/topic/2519/t/MicroPlasmin-Phase-IIb-Trial.html ]]> feeds@yuku.com (ditchthevit) http://floatertalk.yuku.com/topic/2519 Fri, 26 Dec 2008 19:29:55 GMT <![CDATA[ What is Pharmacolgic Vitreolysis? ]]> http://floatertalk.yuku.com/topic/2518/t/What-is-Pharmacolgic-Vitreolysis-.html
www.escrs.org/PUBLICATIONS/EUROTIMES/06june/pdf/Pharmacologicvitreolysis.pdf


PHARMACOLOGIC vitreolysis is a new therapy that could greatly facilitate vitreoretinal surgery today, and offer the possibility of preventing... ]]> feeds@yuku.com (ditchthevit) http://floatertalk.yuku.com/topic/2518 Fri, 26 Dec 2008 18:39:40 GMT <![CDATA[ Important Reply from Dr Sebag ]]> http://floatertalk.yuku.com/topic/2405/t/Important-Reply-from-Dr-Sebag.html I emailed Dr Sebag again about the current research that is being conducted at the DEI. I said that I felt that pharmacolgic vitreolysis is probably the most advanced research that is being conducted currently, and that this whole area offered the best hope for us. I asked him if he felt that the research he is currently involved in would help in the search for the cure for floaters, and also if money was raised where would it be best to donate it. Although the answer is quite vague,... ]]> feeds@yuku.com (ditchthevit) http://floatertalk.yuku.com/topic/2405 Tue, 09 Sep 2008 14:11:40 GMT <![CDATA[ Vitreous problems causes Cataracts - Could enzymatic vitrectomy get ussual for everybody in some years? ]]> http://floatertalk.yuku.com/topic/2370/t/Vitreous-problems-causes-Cataracts--enzymatic-vitrectomy--us.html Oxygen near lens linked to cataracts in eye surgery patients
image
Removal of jelly-like substance appears to accelerate cataract formation
image
By Jim Dryden
feeds@yuku.com (weba) http://floatertalk.yuku.com/topic/2370 Thu, 31 Jul 2008 13:20:15 GMT <![CDATA[ injectables to REPLACE vitrectomy? ]]> http://floatertalk.yuku.com/topic/2363/t/injectables-to-REPLACE-vitrectomy-.html
According to study results, the 125 µg dose was the most effective concentration of the drug; 10 of the 32 patients in the 125 µg group had achieved... ]]> feeds@yuku.com (loulou) http://floatertalk.yuku.com/topic/2363 Mon, 28 Jul 2008 17:31:19 GMT <![CDATA[ News July 2008 - Microplasmin Positive Results in Vitrectomy in 2B Trial. ]]> http://floatertalk.yuku.com/topic/2362/t/News-July-2008-Microplasmin-Positive-Results--Vitrectomy--2B.html ThromboGenics reports positive results from phase 2b trial of microplasmin in vitrectomy

LEUVEN, Belgium - ThromboGenics has announced positive results from a phase 2b trial evaluating the safety and efficacy of microplasmin in vitrectomy.

The randomized, double-masked, placebo-controlled, dose-ranging MIVI III (Microplasmin for vitreous injection) trial evaluated three preoperative doses of microplasmin - 25 µg, 75 µg and 125 µg - vs.... ]]> feeds@yuku.com (weba) http://floatertalk.yuku.com/topic/2362 Mon, 28 Jul 2008 11:59:55 GMT <![CDATA[ 2008 Very Good Enzymatic Vitrectomy News ]]> http://floatertalk.yuku.com/topic/2346/t/2008-Very-Good-Enzymatic-Vitrectomy-News.html Guys, I read that they have been several improvement in Enzymatic Vitrectomy recently. I post some articles in spanish and english to share...
As I see, there are some advances in Spain, Ireland, USA and Germany in... ]]> feeds@yuku.com (weba) http://floatertalk.yuku.com/topic/2346 Thu, 10 Jul 2008 19:12:12 GMT <![CDATA[ Microplasmin (Trombogenics, Leuven, Belgium) ]]> http://floatertalk.yuku.com/topic/2293/t/Microplasmin-Trombogenics-Leuven-Belgium-.html
http://revophth.com/index.asp?page=1_13827.htm

Why here and not in the Alternative Treatments section? Because AFAIK vitreolisis doesn't solve floaters issue at all - it actually causes massive floaters later in time as depolymerized particles bulk up together again. However if applied prior to vitrectomy this procedure can substantially decrease (or even completely eliminate) the risk of retinal tear/detachment.
]]> feeds@yuku.com (Sadysta) http://floatertalk.yuku.com/topic/2293 Thu, 22 May 2008 23:01:39 GMT