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Dec 30 11 1:15 AM
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Dec 30 11 4:12 AM
fishmoon wrote:I am sorry to hear this stringyeye for a less than ideal outcome. I am not exactly sure how post-op debris floaters look like but if what you see are opaque dark strands, I doubt it is blood floaters. Blood floaters, from what I have read on these forums, are free moving tiny specks of debris. There is also a difference in floaters due to blood vs floaters due to inflammation. Blood floaters are due to minor/major hemorrhages and usually disappear from reports on these forums. I have not come across any person on these forums with description of inflammation floaters (WBC/pus/exudate etc) so I do not know. I am missing this info, was your PVD induced?I really hope that these are clumped blood floaters and will disappear. And even if it is some other debris, I hope the movement of eyes fluide via trabecular meshwork and Schlemm's canal or diffusion via uveoscleral outflow will filter these out. Please keep us updated.
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Dec 31 11 8:39 AM
Dec 31 11 9:44 AM
fishmoon witrectotom y rote:ft yu, t hi of hathaye this way: the suspensory ligament of the lens separates the vitreou body from the aqueous humor. Suspensory ligament is formed from the hyaloid membrane. Hyaloid membrane forms zonule of Zinn and that contains suspensory ligament of lens. Anterior to the ligament is aqueous humor secreted by the ciliary body. I think the vitreous/saline can diffuse through the ligament into the anterior/posterior chamber, which itself is anterior to the lens. Vitreous cavity is not fully isolated. How do I know that? I know that people who get intermediate uveitis, one of the cardinal symptoms is floaters! Floaters are almost always due to shadows in vitreous (not aqueous because optics dont allow their shadows to form on retina). So this means vitreous is not "isolated" but things can go into it. Look at anatomy of eye here, http://www.oakparkoptomet...ye-care/anatomy-a-vision You can see clearly that ciliary body which produces aqueous is posterior to suspensory ligament as well and is in touch with vitreous. Vitreous itself truly does not have a blood supply, but the retina it closely attaches to has rich blood supply and there is no doubt that chemicals/drugs can diffuse OUT of the blood vessels into the vitreous. My destroyed vitreous is almost certainly the RESULT of accutane that I took. Either due to direct effects on vitreous or indirect effects on retina, accutane has liquified some part of my vitreous, hence my floaters. So I am positive that very small amounts of contraceptive or anti-depressive drugs DO enter the vitreous, vitreous is not a closed system. Another evidence is that after vitrectomy the saline is replaced by the aqueous because some part of clilary body which secrets the aqueous is posterior to the lens as well. How do drugs entering the vitreous change collagen conformation? Easy. Electrostatic charges, changing solubulity product, changing protein confirmation etc etc, so many ways for these drugs to interact with the vitreous proteins and change their confirmation to form precipitates that we see as floaters. Hope this helped.
Dec 31 11 6:44 PM
Ftyu wrote:fishmoon witrectotom y rote:ft yu, t hi of hathaye this way: the suspensory ligament of the lens separates the vitreou body from the aqueous humor. Suspensory ligament is formed from the hyaloid membrane. Hyaloid membrane forms zonule of Zinn and that contains suspensory ligament of lens. Anterior to the ligament is aqueous humor secreted by the ciliary body. I think the vitreous/saline can diffuse through the ligament into the anterior/posterior chamber, which itself is anterior to the lens. Vitreous cavity is not fully isolated. How do I know that? I know that people who get intermediate uveitis, one of the cardinal symptoms is floaters! Floaters are almost always due to shadows in vitreous (not aqueous because optics dont allow their shadows to form on retina). So this means vitreous is not "isolated" but things can go into it. Look at anatomy of eye here, http://www.oakparkoptomet...ye-care/anatomy-a-vision You can see clearly that ciliary body which produces aqueous is posterior to suspensory ligament as well and is in touch with vitreous. Vitreous itself truly does not have a blood supply, but the retina it closely attaches to has rich blood supply and there is no doubt that chemicals/drugs can diffuse OUT of the blood vessels into the vitreous. My destroyed vitreous is almost certainly the RESULT of accutane that I took. Either due to direct effects on vitreous or indirect effects on retina, accutane has liquified some part of my vitreous, hence my floaters. So I am positive that very small amounts of contraceptive or anti-depressive drugs DO enter the vitreous, vitreous is not a closed system. Another evidence is that after vitrectomy the saline is replaced by the aqueous because some part of clilary body which secrets the aqueous is posterior to the lens as well. How do drugs entering the vitreous change collagen conformation? Easy. Electrostatic charges, changing solubulity product, changing protein confirmation etc etc, so many ways for these drugs to interact with the vitreous proteins and change their confirmation to form precipitates that we see as floaters. Hope this helped.My friend, I appreciate your reply. Before these things came, during 7 years I took an antidepressant to have some control over panic attacks, a small dose. I was even quitting when it appeared. First in one eye, 10 days later, in the other. Needless to say doctor prescribed an extra dose to help me in the first times - Some 4 months taking a quadruple dose and added xanax. Floaters stayed the same for 2 years. This year however I could notice some increase of amoeba-like strands, branching from the original floaters. I know people who have taken tonnes of chemicals their whole life and have their vision clear. You have suspicions about Accutane. Sapiens mentioned SSRIs. But all we have is beliefs, we really don't know what's going in our eyes. Everyone I read has a personal explanation ranging from vitamins to computer monitors and I no longer know what to believe in. What do I have to change? Today I just talked with a friend and he told me has floaters and described them. In fact he doesn't care and even "enjoys playing with them". He never took anything besides beer and does not need glasses. I don't understand. Maybe chemicals accelerated something, but as the time passes by, I feel that we would got these anyway. As the matter a fact, I remember squinting my eyes facing a lamp til when I was a kid and recall seeing things that looked like cells. When I do that now, all the floaters look just like those cells but now in clogged strands and balls. It's like these have always been here and now they clumped and I see them. FOV looks like the only practical hope.
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Dec 31 11 9:15 PM